A suburban couple's ordinary lives are rocked by the sudden discovery that their children possess mutant powers. Forced to go on the run from a hostile government, the family joins up with an underground network of mutants and must fight to survive.
Reeva prepares to carry out her plan for the Inner Circle, but not everyone is on the same page. Reed struggles to manage his powers and the family realizes that without enough of the serum, it's only a matter of time before he completely loses control. Frustrated and egged on by Benedict Ryan, Jace and the Purifiers are on the attack, but for Jace, things aren't as black and white as they once were.